Learn about TRK fusion cancer and how it differs from
Whether you’re a patient or a caregiver, this
site offers valuable
information to help
you on your journey.
TRK fusion cancer is a term used to describe a variety of common and rare cancers that are caused by a change to the NTRK gene called a fusion. During this fusion, an NTRK gene joins together, or fuses, with a different gene.
This joining results in the activation of certain proteins (TRK fusion proteins), which can cause cancer cells to multiply and form a tumor.
Some genomic markers tend to cause tumors in certain
areas of the body. In TRK fusion cancer, the same
marker (NTRK gene fusion) can cause cancer to begin in
a different part of the body from patient to patient.
The idea of TRK fusion cancer may be new to you and
you may understand cancer in terms of an area of the
body, such as lung or colon cancer. Having TRK fusion
cancer doesn’t change your original diagnosis; it just
means that your tumor’s driver is an NTRK gene fusion.